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This letter reports an ab initio study on
2020-04-28
This letter reports an ab initio study on the X peaks of PES by including the SO effect. The multiplet split energies are calculated with the SO-MCQDPT2 method [21], and the so-called pole strengths are evaluated to simulate the relative intensities. The results are compared with the experimental PE
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The lack of robust immunocompetent animal models permissive
2020-04-28
The lack of robust immunocompetent animal models permissive for HCV makes it hard to assess if the quantity and quality of vaccine-induced immunity is sufficient to confer protection. Thus, it is difficult to predict to what extent antibody responses induced by current vaccination approaches, includ
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Eggs have been recognized as an
2020-04-28
Eggs have been recognized as an important contributor of functional ingredients for humans [3]. Egg yolk is composed of various biologically active proteins. The water-soluble proteins of egg yolk have been examined for their functional effects on longitudinal bone growth during the growth period in
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you want to be br Author Contributions br Acknowledgments br
2020-04-28
Author Contributions Acknowledgments Introduction Osteoporosis is a common bone disease that frequently leads to disruption of the alveolar and systemic bones with age. Novel osteoanabolic strategies to treat osteoporotic bone loss or augment fracture repair efficiently are desired. Since b
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Introduction Determining how genes function together as biol
2020-04-28
Introduction Determining how genes function together as biological systems is a defining challenge of the genomic era. While genome sequences reveal the DNA blueprint of organisms, deciphering how this blueprint leads to biological function is challenging due in large part to the complexity of prot
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Twin studies have shown that P has moderate heritability
2020-04-28
Twin studies have shown that P has moderate heritability. Zuckerman (1989) reviewed the earlier studies of P or related traits and found a median heritability of 0.51. However, twin studies using an Eysenckian P scale have tended to estimate somewhat lower heritabilities than this, in the range 0.36
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br Localization of D receptors
2020-04-28
Localization of D2 receptors in striatum One characteristic of D2Rs that has complicated their study is their expression in multiple neuronal populations within striatum, both pre- and postsynaptically (Beaulieu and Gainetdinov, 2011). In addition to spiny projection neurons (SPNs), which are the
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Carbazole could be recrystallised from ethyl
2020-04-28
Carbazole could be recrystallised from ethyl acetate to provide bright red crystals suitable for single crystal X-ray diffraction (see ). The first crop showed had crystallised preferentially as the ()-isomer (A). Examining the single crystal X-ray data of it was interesting to find that the N2C1
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In cancer interactions between the transformed cancer cells
2020-04-28
In cancer, interactions between the transformed cancer tryptophan hydroxylase and other cell types recruited to the tumor are important. Tumor associated macrophages provide cancer cells with a suitable low-grade inflammatory milieu including growth promoting factors. Our results suggest a novel pro
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The present study is the first time to investigate
2020-04-28
The present study is the first time to investigate the effect of piperine on intestinal sterol transporters and enzymes in the small intestine. NPC1L1 is a sterol transporter responsible for taking up cholesterol from the lumen to enterocytes (Davis et al., 2004). ACAT2 is an enzyme, which esterifie
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Increased leukocyte trafficking and infiltration of
2020-04-28
Increased leukocyte trafficking and infiltration of the vascular wall are thought to provide a key stimulus for SMC activation and subsequent neointima formation in response to vascular injury [19], [20]. The essential trigger regulating the accumulation of leukocytes in the vessel wall is the upreg
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br Phenotypic responses alkylation induced cell death and
2020-04-27
Phenotypic responses: alkylation-induced cell death and mutagenesis E. coli alkB mutants were isolated in a screen for strains specifically sensitive to the cytotoxicity of MMS but not UV-irradiation. This was the first indication that the AlkB protein is a primary cellular defence against alkyla
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DDR upregulation in patients with kidney diseases such
2020-04-27
DDR1 upregulation in patients with kidney diseases such as lupus nephritis and Goodpasture\'s syndrome [8] as well as in animal models of kidney injury [7], [8], [18] suggests that DDR1 plays an important role in kidney disease. Studies in various mouse models of kidney injury indicate that DDR1 del
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One of the most frequent
2020-04-27
One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are apelin regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and 53%, respectively, hav
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br Asb Proteins and Mitochondrial Function Mitochondria are
2020-04-27
Asb Proteins and Mitochondrial Function Mitochondria are intracellular organelles in eukaryotic IKK-16 hydrochloride sale and are the main sites of oxidative phosphorylation and ATP production. In addition, mitochondria serve as signal transduction docking stations in pyroptosis and regulate a p
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